Etizolam vs Clonazepam

Etizolam vs. Clonazepam

Etizolam vs. Clonazepam: A Must-To-Know Comparison Guide

Anxiety disorders are no joke. The mental disorder is real and the symptoms are known to affect overall health of a sufferer. Fortunately, with the advancements in medical sector, we have been able to treat anxiety disorders and the annoying symptoms exerted by them.

Medicines belonging to the benzodiazepine class of medicines are generally prescribed to treat anxiety disorders. However, there are medicines from thienodiazepine class of medicines useful in treating anxiety disorders. In this guide, we are going to talk about a benzodiazepine – Clonazepam and a thienodiazepine – Etizolam. We will majorly be discussing their differences, and also talk about the similarities these two medications share.

What is Clonazepam? How does it work?

It is an anti-anxiety medicine from benzodiazepine class. Diazepam (Valium), Lorazepam (Ativan), Alprazolam (Xanax) are some of the popular members of the family. Clonazepam works by improving the effects of gamma-aminobutyric acid (GABA) – a neurotransmitter used by the nerve cells to communicate amongst them. GABA prohibits excessive brain activity which further leads to reduced anxiety symptoms. Clonazepam is also used in the treatment of panic disorders and certain types of seizures. It is approved by the FDA in June 1975 for medical usages.

What is Etizolam? How does it work?

It is a thienodiazepine class of drug and often known as a benzodiazepine analogue. It is because the chemical structure is quite similar to majority of medicines from the benzodiazepine family. Etizolam is known to have anti-anxiety effects along with sedative, hypnotic, amnesic, anticonvulsant, anxiolytic, and muscle relaxant properties. Etizolam shows major closeness to the benzodiazepine triazolam. It is subjected to abuse and thus it is available only with prescription and must be used for short period of time.

Etizolam is a powerful thienodiazepine with properties quite similar to benzodiazepines. However, it is ten times stronger than diazepam. It is because of its deep land faster sedation effect. Users have reported significant reduction in anxiety symptoms, enhanced relaxation, sedation, loss of inhibition after taking Etizolam 1mg tablets.

Etizolam vs. Clonazepam

  • Both the medicines are used in the treatment of anxiety disorders. However, Etizolam has low sedation strength as compared to Clonazepam. However, the final decision should be made by your doctor in order to select the best medicines to control your anxiety symptoms.
  • Clonazepam takes approximately 20 to 60 minutes. The peak plasma concentration is attained within 1 to 4 hours post ingestion. This medicine stays in your system for about 6 to 9 days.
  • Etizolam gets absorbed in the gastrointestinal tract quickly and reaches peak plasma concentration within 30 minutes to 2 hours. The medication has a half-life of 3.5 hours. Its active metabolite alpha-hydroxyetizolam has half-life of over 8 hours. Etizolam is intensely effective after 3 to 4 hours post consumption and the effects can last from 6 to 8 hours.
  • Etizolam and Clonazepam cause dependence in the user. However, Clonazepam does it even when it is consumed in prescribed dosage strength whereas Etizolam dependence occurs when it is consumed in large dosages for longer time span.

Can Etizolam and Clonazepam be consumed together?

This combination is not preferred because it increases the risk of developing adverse effects. The risk of sedation also increases and hence taking Etizolam with Clonazepam is not recommended.

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